Former leaders of Khmer Rouge convicted of genocide, war crimes

The last surviving members of the Khmer Rouge have been sentenced to life in prison for crimes against humanity under an international tribunal. The process toward justice has been long and winding in the decades since Pol Pot left power in the 1970s. Full Story Here CS Monitor November 18, 2018 6:56 am Support Us

Saudi prosecutor will seek the death penalty for Khashoggi’s killers

Saudi Arabia’s top prosector announced at a press conference he will seek the death penalty for five suspects charged with orchestrating the murder of Saudi writer Jamal Khashoggi. The prosecutor stated the killing was a spontaneous action and not premeditated. Full Story Here CS Monitor November 18, 2018 6:42 am Support Us

After Rohingya refuse to go, Bangladesh puts return plans on hold

On Nov. 15, Bangladesh had planned on beginning the repatriation of 700,000 Rohingya Muslims to Myanmar, where they had previously faced violence. But the Rohingya people – fearing for their own safety – refused to return when the buses appeared. Full Story Here CS Monitor November 18, 2018 6:42 am Support Us

A ‘circular economy’ appeals to cities wanting to reduce carbon footprints

From Amsterdam to Barcelona, European cities are working hard to reduce their carbon emissions. But some of the necessary high-tech measures, such as solar panels and electric cars, are expensive, and officials worry that those unable to pay will be excluded. Full Story Here CS Monitor November 18, 2018 6:26 am Support Us

A legal takedown of genocide

A verdict against two high-level Khmer Rouge leaders helps spread the application of human-rights law and could prevent such atrocities. Full Story Here CS Monitor November 18, 2018 6:11 am Support Us

Giving thanks for Native American words

The list of words that English has adopted from Native American languages could go on for hundreds of pages and include vocabulary in the spheres of technology, politics, and insult. Full Story Here CS Monitor November 18, 2018 6:11 am Support Us

Reaching

At a time when questions of identity are front and center, today’s column is a poem that offers a deeper, spiritual sense of what we all are as God’s eternally loved children. Full Story Here CS Monitor November 18, 2018 5:56 am Support Us

Bystander training

An incident on a train in Germany points to how things have changed there. Full Story Here CS Monitor November 18, 2018 5:56 am Support Us

The living Word of the Bible

In light of International Day of the Bible this Sunday, today’s contributor shares how understanding the inspired Word of the Bible has been an invaluable guide and source of strength throughout her life. Full Story Here CS Monitor November 18, 2018 5:42 am Support Us

Black Friday means vinyl: Watch for these releases

If you’re interested in scoring some gifts on Record Store Day for yourself or music-loving friends on your holiday shopping list, here are a few new releases bound to stir excitement. Full Story Here CS Monitor November 18, 2018 5:26 am Support Us

Horse sense for politics

Only by not resorting to violence can you develop a relationship built on trust and respect. Full Story Here CS Monitor November 18, 2018 4:41 am Support Us

Can communities learn to live with wildfire?

As highly destructive wildfires become increasingly commonplace, communities throughout the West are having to shift their focus from prevention to adaptation and resilience. Full Story Here CS Monitor November 17, 2018 7:11 am Support Us

May’s ministers resign over Brexit, new fears of no confidence vote

As the divorce deal Britain negotiated with the European Union gains approval and heads to the British Parliament for a vote, Pro-Brexit ministers unhappy with the outcome are resigning. The future of Prime Minister May’s government hangs in the balance.  Full Story Here CS Monitor November 17, 2018 6:56 am Support Us

Chinese officials defensive over Muslim re-education camps

Chinese officials have responded to a letter from 15 foreign ambassadors, spearheaded by Canada, expressing concern over the incarceration of thousands of Chinese Muslims, saying the letter contained “unreasonable requests” and was based on hearsay.  Full Story Here CS Monitor November 17, 2018 6:41 am Support Us

Behind the surprising surge of hope for US criminal justice reform

Criminal justice reform is something people on the right and left agree is desperately needed but agreed was unlikely to happen. Suddenly, this week, advocates say they have hope again – and an unlikely champion. Full Story Here CS Monitor November 17, 2018 6:26 am Support Us

Hundreds of Central American migrants arrive in Tijuana

In the first contingent of several different migrant caravans, hundreds of Central Americans have reached the US-Mexico border. Mexico has offered refuge, asylum, and work visas to the migrants, but some migrants remain intent on making it over the US border. Full Story Here CS Monitor November 17, 2018 6:11 am Support Us

Marine, novelist, dad: a conversation with Elliot Ackerman

Three-time novelist Elliot Ackerman’s latest book, “Waiting for Eden,” explores the multiple dimensions of veterans’ lives after war, and what it means to love someone despite limitations and challenges. Full Story Here CS Monitor November 17, 2018 6:11 am Support Us

In global refugee flow, Canada finds a surprising solution to a labor shortage

It’s widely understood that refugees need help, but sometimes they also can lend a helping hand. A program that places skilled refugees in jobs in Canada helps resettle uprooted people and may help fill a labor shortage in the northern nation. Full Story Here CS Monitor November 17, 2018 5:56 am Support Us

Watch out, 2020: Young voters are on the rise

Youth turnout this year was the highest it’s been in at least 25 years, and the vast majority of those new voters were Democratic. Full Story Here CS Monitor November 17, 2018 5:56 am Support Us

The FDA shields youths from vaping

The agency’s proposed rules aim to reverse an alarming spike in use of electronic cigarettes among teens. They also declare the need to guard the innocence of youth. Full Story Here CS Monitor November 17, 2018 5:41 am Support Us

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

CRISPR-Cas systems provide microbes with adaptive immunity to infectious nucleic acids and are widely employed as genome editing tools. These tools use RNA-guided Cas proteins whose large size (950 to 1400 amino acids) has been considered essential to their specific DNA- or RNA-targeting activities. Here we present a set of CRISPR-Cas systems from uncultivated archaea… Read More

In vivo modeling of human neuron dynamics and Down syndrome

Harnessing the potential of human stem cells for modeling the physiology and diseases of cortical circuitry requires monitoring cellular dynamics in vivo. We show that human induced pluripotent stem cell (iPSC)–derived cortical neurons transplanted into the adult mouse cortex consistently organized into large (up to ~100 mm3) vascularized neuron-glia territories with complex cytoarchitecture. Longitudinal imaging… Read More

Comment on “Predicting reaction performance in C-N cross-coupling using machine learning”

Ahneman et al. (Reports, 13 April 2018) applied machine learning models to predict C–N cross-coupling reaction yields. The models use atomic, electronic, and vibrational descriptors as input features. However, the experimental design is insufficient to distinguish models trained on chemical features from those trained solely on random-valued features in retrospective and prospective test scenarios, thus… Read More

SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

One-carbon metabolism generates the one-carbon units required to synthesize many critical metabolites, including nucleotides. The pathway has cytosolic and mitochondrial branches, and a key step is the entry, through an unknown mechanism, of serine into mitochondria, where it is converted into glycine and formate. In a CRISPR-based genetic screen in human cells for genes of… Read More

Templated nanofiber synthesis via chemical vapor polymerization into liquid crystalline films

Extrusion, electrospinning, and microdrawing are widely used to create fibrous polymer mats, but these approaches offer limited access to oriented arrays of nanometer-scale fibers with controlled size, shape, and lateral organization. We show that chemical vapor polymerization can be performed on surfaces coated with thin films of liquid crystals to synthesize organized assemblies of end-attached… Read More

Dietary fat: From foe to friend?

For decades, dietary advice was based on the premise that high intakes of fat cause obesity, diabetes, heart disease, and possibly cancer. Recently, evidence for the adverse metabolic effects of processed carbohydrate has led to a resurgence in interest in lower-carbohydrate and ketogenic diets with high fat content. However, some argue that the relative quantity… Read More

The gut microbiota at the intersection of diet and human health

Diet affects multiple facets of human health and is inextricably linked to chronic metabolic conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. Diet is a key… Read More

Swifter, higher, stronger: Whats on the menu?

The exploits of elite athletes delight, frustrate, and confound us as they strive to reach their physiological, psychological, and biomechanical limits. We dissect nutritional approaches to optimal performance, showcasing the contribution of modern sports science to gold medals and world titles. Despite an enduring belief in a single, superior “athletic diet,” diversity in sports nutrition… Read More

Heterobiaryl synthesis by contractive C-C coupling via P(V) intermediates

Heterobiaryls composed of pyridine and diazine rings are key components of pharmaceuticals and are often central to pharmacological function. We present an alternative approach to metal-catalyzed cross-coupling to make heterobiaryls using contractive phosphorus C–C couplings, also termed phosphorus ligand coupling reactions. The process starts by regioselective phosphorus substitution of the C–H bonds para to nitrogen… Read More

A time to fast

Nutrient composition and caloric intake have traditionally been used to devise optimized diets for various phases of life. Adjustment of meal size and frequency have emerged as powerful tools to ameliorate and postpone the onset of disease and delay aging, whereas periods of fasting, with or without reduced energy intake, can have profound health benefits.… Read More