Hormone therapy may improve some symptoms of autism

Two studies suggest that suppressing or boosting the hormone vasopressin may help communication skills and social interactions in autistic children and men Full Story Here New Scientist.com May 13, 2019 1:25 pm Support Us

Introducing this week’s new-look New Scientist magazine

Welcome to the redesigned New Scientist, with a brighter, fresher feel. All your old favourites are still here and we now have more columns and puzzles. We hope you enjoy it Full Story Here New Scientist.com May 13, 2019 1:25 pm Support Us

Reporting in Xinjiang: ‘A war zone with no war’

As Ramadan starts, Muslims in Xinjiang, China, face tight restrictions. Our reporter gives a firsthand account of China’s crackdown in Xinjiang.  Full Story Here CS Monitor May 13, 2019 1:11 pm Support Us

North Korea puts diplomacy at risk with another weapons launch

North Korea has launched weapons twice in five days as a possible signal that Kim Jong Un’s regime is turning away from diplomacy. South Korea said it is working with the United States to determine the types of weapons that were fired. Full Story Here CS Monitor May 13, 2019 12:25 pm Support Us

To end painful memories

After suffering from PTSD for years, today’s contributor turned to God in heartfelt prayer. The realization that God’s peace and goodness are permanent freed her from the mental baggage without a long recovery or rebuilding process. Full Story Here CS Monitor May 13, 2019 12:10 pm Support Us

Mother’s love and loving our mothers

After more than a century of official mother’s days in the U.S., much has changed for mothers. But not their central role as influencers of future generations. Full Story Here CS Monitor May 13, 2019 12:10 pm Support Us

New kind of battery make solar, wind worth its salt

A German energy company is testing the use of salt to store heat. If successful, the system could help solve a problem posed by unreliable renewable energy sources, such as wind and solar. Full Story Here CS Monitor May 13, 2019 11:56 am Support Us

When life defies our efforts to plan

When her “on-track” life took an unexpected turn, today’s contributor panicked. But through prayer she came to realize that “when we humbly listen for God’s direction, the voices of fear and doubt are quieted, and we come to see the future as not a void of uncertainty but a promise of abundant blessings.” Full Story… Read More

Why Sudan is a pivot for democracy

The battle for democracy in both Africa and the Arab world is playing out in the protests in Khartoum against military rule. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

Why US-China trade talks are about more than trade

President Trump is poised to boost tariffs on China. And in a rare bipartisan moment, top Democrats also call for a tough stance in trade talks. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

Crucial midterm test: Will Filipino voters back Duterte’s allies?

In the Philippines, 43,500 candidates are vying for around 18,000 congressional and local posts in Monday’s elections. The outcome could show if President Rodrigo Duterte’s authoritarian-style leadership still has popular support. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

Learn more about Love

Today’s contributor shares how a growing understanding of God as Love has showed her how we can all express a more tender, patient, and effective mothering love for others, as well as for our children. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

More to ‘redaction’ than meets the eye

Attorney General William Barr’s redactions to the Mueller report were intended to leave out information, but there’s still plenty there to learn. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

San Francisco may become first U.S. city to ban facial recognition

If San Francisco adopts a ban, other cities, states, or even Congress could follow, with lawmakers looking to curtail government surveillance. But local critics say the technology is useful for police investigations in high-crime areas. Full Story Here CS Monitor May 13, 2019 10:41 am Support Us

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex

During corticogenesis, distinct subtypes of neurons are sequentially born from ventricular zone progenitors. How these cells are molecularly temporally patterned is poorly understood. We used single-cell RNA sequencing at high temporal resolution to trace the lineage of the molecular identities of successive generations of apical progenitors (APs) and their daughter neurons in mouse embryos. We… Read More

Measles and the canonical path to elimination

All World Health Organization regions have set measles elimination goals. We find that as countries progress toward these goals, they undergo predictable changes in the size and frequency of measles outbreaks. A country’s position on this “canonical path” is driven by both measles control activities and demographic factors, which combine to change the effective size… Read More

Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies

Eukaryotic genes are regulated by multivalent transcription factor complexes. Through cooperative self-assembly, these complexes perform nonlinear regulatory operations involved in cellular decision-making and signal processing. In this study, we apply this design principle to synthetic networks, testing whether engineered cooperative assemblies can program nonlinear gene circuit behavior in yeast. Using a model-guided approach, we show… Read More

Site-selective enzymatic C-H amidation for synthesis of diverse lactams

A major challenge in carbon-hydrogen (C-H) bond functionalization is to have the catalyst control precisely where a reaction takes place. In this study, we report engineered cytochrome P450 enzymes that perform unprecedented enantioselective C-H amidation reactions and control the site selectivity to divergently construct β-, -, and -lactams, completely overruling the inherent reactivities of the… Read More

Particulate methane monooxygenase contains only mononuclear copper centers

Bacteria that oxidize methane to methanol are central to mitigating emissions of methane, a potent greenhouse gas. The nature of the copper active site in the primary metabolic enzyme of these bacteria, particulate methane monooxygenase (pMMO), has been controversial owing to seemingly contradictory biochemical, spectroscopic, and crystallographic results. We present biochemical and electron paramagnetic resonance… Read More

Not so fast

Full Story Here Science Mag May 9, 2019 12:11 pm Support Us

A keener eye

Full Story Here Science Mag May 9, 2019 12:11 pm Support Us

Response

Full Story Here Science Mag May 9, 2019 12:11 pm Support Us

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes

Muscarinic acetylcholine receptors are G protein–coupled receptors that respond to acetylcholine and play important signaling roles in the nervous system. There are five muscarinic receptor subtypes (M1R to M5R), which, despite sharing a high degree of sequence identity in the transmembrane region, couple to different heterotrimeric GTP-binding proteins (G proteins) to transmit signals. M1R, M3R,… Read More

New Products

Full Story Here Science Mag May 9, 2019 12:11 pm Support Us